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  1. Various types of lower extremity orthopedic surgeries can cause severe postoperative pain in elderly patients. Achieving adequate pain control while minimizing the use of opioids is advantageous, as it helps r...

    Authors: Yinghua Gu, Yan Li, Wenxun Liu, Xin Liu and Qingshan Ye
    Citation: Perioperative Medicine 2025 14:58
  2. Recent attention has focused on intraoperative hypotension (IOH) and hemodynamic instability. This enhanced awareness to limit IOH, combined with fluid restriction and increased vasopressor use, has been assoc...

    Authors: Amy Yerdon, Ken Taylor, Katie Woodfin, Ryan Richey, Susan McMullan and Desirée Chappell
    Citation: Perioperative Medicine 2025 14:57
  3. Volume-controlled ventilation (VCV) and pressure-controlled ventilation (PCV) are commonly used in laparoscopic surgery in the Trendelenburg position, and pressure-controlled ventilation volume guaranteed (PCV...

    Authors: Cui Wen, Yi Qi, Yingying Xiang, Qianyun Pang, Jingyu Xiao and Ran An
    Citation: Perioperative Medicine 2025 14:56
  4. Arrhythmias are a frequent complication in the postoperative period following surgical procedures. This study aims to investigate the incidence and contributing factors of arrhythmias in elderly patients with ...

    Authors: Xiaoyu Chen, Yan Wu and Xiaofang Zheng
    Citation: Perioperative Medicine 2025 14:55
  5. Despite advancements in anesthesia, the anesthetic outcomes in pediatric tonsillectomy remain largely underexplored, notably in resource-limited healthcare systems. This study aimed to assess the anesthetic ou...

    Authors: Ramzi Shawahna, Shahed Radwan, Dana Alyan, Rawand Obaid, Suha Sholi, Mohammad Jaber, Iyad Maqboul, Hatim Hijaz and Samer Bustame
    Citation: Perioperative Medicine 2025 14:54
  6. Elderly patients are a vulnerable group with high perioperative risks. Thus, reducing the duration of anesthesia is important. Remimazolam is a benzodiazepine sedative commonly used for the induction and maint...

    Authors: Yang Wan-jun, Geng Zhi-long, Gao Yuan-yuan, Cui Chao-yuan, Chen Zheng-ze, Tian Zi-wei, Guo Xi-lin, Zhang Ya-nan, Wang Lu, Huo Rui, Ma Chen-wei and Niu Jing
    Citation: Perioperative Medicine 2025 14:53
  7. Epidural morphine is considered one of the most potent drugs used for postoperative analgesia; however, its side effects are dose-related and exaggerated in elderly people. In this study, we aimed to determine...

    Authors: Muhammad Shawqi, Sahar Abdel-Baky Mohamed, Essam Sharkawy and Diab Hetta
    Citation: Perioperative Medicine 2025 14:52
  8. Surgical gloves are a medical product and a cornerstone of prevention from surgical site infections and staff injury. This study aimed to investigate the integrity of surgical gloves worn by scrub nurses durin...

    Authors: Leon Euler-Schmidt, Artur Barsumyan, Jan Adriaan Graw, Christian Soost, Yvonne Stephan and Rene Burchard
    Citation: Perioperative Medicine 2025 14:51
  9. Perioperative management in diabetic patients is important since their postoperative mortality and morbidity are higher than that of non-diabetic patients, which will exacerbate the burden on public health. We...

    Authors: Jiangru Kang, Xin Chai, Tao Jia, Huiru Hu, Rong Fu and Huang Nie
    Citation: Perioperative Medicine 2025 14:50
  10. Ciprofol is an intravenous anesthetic agent which in low doses produces sedation. It was developed via structural modification of propofol. Ciprofol is claimed to reduce respiratory depression. The object of t...

    Authors: Yanjing Zhang, Danru Xie, Feifei Li, Mengjiao Che, Yaoheng Yang, Geng Li and Yiwen Zhang
    Citation: Perioperative Medicine 2025 14:49
  11. Extubation refers to removing the breathing tube from the patient’s airway after surgery under general anesthesia with tracheal intubation. Extubation procedures typically take less than 15 min, and if they ta...

    Authors: Gemechisa Akuma Wayesa, Mitiku Berhanu Wedajo, Wondu Reta Demissie, Admasu Belay Gizaw, Assefa Hika Gudeta and Guteta Gudina Gula
    Citation: Perioperative Medicine 2025 14:48
  12. Good functional recovery after cardiac surgery can be reported as ‘days alive and out of hospital’ in the first 30 days after a procedure (DAOH30) and ‘days at home’ in the first year (DAH365), which integrate se...

    Authors: M. Abdelmonem, M. Elsayed, D. Awadallah, O. Don, R. H. Bennett, O. G. Mackay, S. Pookayil, C. Archer, M. Mahgoub and M. J. Bennett
    Citation: Perioperative Medicine 2025 14:46
  13. Importance Previous evidence has indicated that N-terminal pro-B-type natriuretic peptide (NT-proBNP) is associated with postoperative acute kidney injury (AKI). However, the association between preoperative NT-p...

    Authors: Zefei Zhang, Ziyu Zheng, Huang Nie, Hailong Dong and Chong Lei
    Citation: Perioperative Medicine 2025 14:45
  14. We aimed to probe the clinical value of N-terminus pro-brain natriuretic peptide (NT-proBNP), myeloperoxidase (MPO), and neutrophil lymphocyte ratio (NLR) combined with echocardiography in the prediction of ma...

    Authors: Jianping Liu, Apei Zhou, Meiduan Zheng, Ling Wang and Ping Zeng
    Citation: Perioperative Medicine 2025 14:44
  15. Gastrointestinal complications (GICs) following cardiac surgery with cardiopulmonary bypass (CPB) significantly impact postoperative recovery and clinical outcomes.

    Authors: Xiaofang Yang, Ning Lu, Luxi Yang, Boxia Li, Wenjun Zhou, Yuanmin Li, Bing Song, Jinqiu Yuan and Wenbo Meng
    Citation: Perioperative Medicine 2025 14:42
  16. Perioperative neurocognitive disorders encompass delayed neurocognitive recovery (dNCR). Emerging evidence suggests that chemokines play a crucial role in the pathogenesis of various cognitive impairment disea...

    Authors: Liu Han, Meng-Meng Dong, Ke Ding, Qing-Chun Sun, Zhen-Feng Zhang, He Liu, Yuan Han and Jun-Li Cao
    Citation: Perioperative Medicine 2025 14:41
  17. Early warning system (EWS) scores are implemented on surgical wards to identify patients at high risk of postoperative clinical deterioration, but its predictive value in older patients is unclear. This study ...

    Authors: Annick Stolze, Lisette Vernooij, Dianne de Korte-de Boer, Markus W. Hollmann, Wolfgang F. F. A. Buhre, Christa Boer and Peter G. Noordzij
    Citation: Perioperative Medicine 2025 14:39
  18. Abdominal surgical patients who have deficient blood volume are at an elevated risk of post-induction hypotension (PIH). New strategies have been adopted, i.e., carotid ultrasound, to evaluate volume status. T...

    Authors: Tao Sun, Kangli Hui, Liwen Ren, Mengtong Han, Xiaoyun Shen, Jingwei Xiong, Hongwei Qi and Manlin Duan
    Citation: Perioperative Medicine 2025 14:38
  19. Postoperative delirium is a prevalent complication in cardiac surgery patients, highlighting the importance of early risk factor identification for optimal management. This study aimed to pinpoint risk factors...

    Authors: Hosein Mahmoudi, Athanasios Chalkias, Ali Moradi, Seyed Tayeb Moradian, Seyed Mohammad Reza Amouzegar and Amir Vahedian-Azimi
    Citation: Perioperative Medicine 2025 14:37
  20. The purpose was to explore the independent risk factors for esophagogastric anastomotic leakage (EGAL) and establish a nomogram.

    Authors: Jiang-shan Huang, Li-tao Yang, Jia-fu Zhu, Qi-hong Zhong, Fei-long Guo, Zhen-yang Zhang and Jiang-bo Lin
    Citation: Perioperative Medicine 2025 14:36
  21. Pulmonary rehabilitation programs for COPD patients are extensively accessible throughout the UK and have demonstrated efficacy in enhancing outcomes, including recovery from exacerbations. Numerous lung cance...

    Authors: Matar Alzahrani, Rajnikant Mehta, Salma Kadiri, Saffana Algaeed, Aya Osman, Mohammed Alsanad, Joan Duda, Fang Gao and Babu Naidu
    Citation: Perioperative Medicine 2025 14:35
  22. Extended stays in the postanesthesia care unit (PACU) pose challenges in high-volume endoscopies. This study investigates the impact of intraoperative fentanyl use on PACU duration, postoperative pain, and fin...

    Authors: Miho Akabane, Kelsey Kukuruza, Timothy Angelotti, Subhas Banerjee and Kazuo Ando
    Citation: Perioperative Medicine 2025 14:33
  23. Carbon dioxide (CO2) accumulation during prolonged painless colonoscopy procedures in patients with obstructive sleep apnea syndrome (OSAS) can lead to an increased incidence of various complications. The disp...

    Authors: Pengxia Wang, Qiuxiang Jiang, Kaihui Li, Yinying Zeng, Zhangxing Chen and Shanshan Liu
    Citation: Perioperative Medicine 2025 14:32
  24. Through bibliometric analysis, this paper summarizes the growing literature and analyses the development trends and hot spots in the research field of the association between intravenous anesthesia and tumors.

    Authors: Fangfang Han, Shi Dong, Zhou Chen, Cheng Ye, Chunlu Dong, Yan Du, Huaqing Shi, Gen Lu and Wence Zhou
    Citation: Perioperative Medicine 2025 14:31
  25. Cerebral blood flow autoregulation is affected by several physiologic and medical factors. Especially arterial carbon dioxide pressures (PaCO2) impact cerebral blood flow. Only extensive changes in end-tidal CO2 ...

    Authors: Philipp Groene, Miriam Rapp, Tobias Ninke, Peter Conzen and Klaus Hofmann-Kiefer
    Citation: Perioperative Medicine 2025 14:30
  26. The National Institute of Academic Anaesthesia (NIAA) is a major UK-based funder of academic anaesthesia and perioperative medicine. It holds two grant rounds per year. Since 2019, research outputs have been c...

    Authors: Naomi Watson and Gudrun Kunst
    Citation: Perioperative Medicine 2025 14:29
  27. Perioperative anxiety is associated with complications during and after surgery, resulting in prolonged hospital stays, and long-term physical and cognitive decline. A prospective observational study was condu...

    Authors: Priya Goyal, Prisha, Joshua S. Chacko, Aman Goyal, Shikha Gupta and Suneet Kathuria
    Citation: Perioperative Medicine 2025 14:27
  28. The induction of spinal anesthesia is often followed by hypotension, which has been associated with post-operative end-organ damage. A timely prediction of spinal anesthesia-induced hypotension (SAIH) paired w...

    Authors: Esmée C. de Boer, Joris van Houte, Catarina Dinis Fernandes, Tom Bakkes, Jens Muehlsteff, R. Arthur Bouwman and Massimo Mischi
    Citation: Perioperative Medicine 2025 14:26
  29. Laparoscopic appendectomy is a common emergency surgical procedure worldwide, known for its benefits of reduced pain, shorter hospital stays, and quicker recovery times. Although postoperative care typically i...

    Authors: Christopher Hendrix, Sarah Swint, Rachel Krawczyk, Tyler Soderling, Jana Alford and John Shellenberger
    Citation: Perioperative Medicine 2025 14:25
  30. Despite the absence of scientific evidence, fasting before percutaneous cardiac catheterization is still recommended to minimize complications. This systematic review and meta-analysis aimed to compare the out...

    Authors: Elsayed Balbaa, Ahmed A. Ibrahim, Mohammad Bazzazeh, Shehroze Tabassum, Shrouk Ramadan, Ahmed Farid Gadelmawla, Abdelrahman Elshimy, Obieda Altobaishat and Mohamed Abuelazm
    Citation: Perioperative Medicine 2025 14:24
  31. Acute postoperative pain management often requires opioid treatment with patient-controlled analgesia (PCA). Non-invasive PCA with a sublingual sufentanil tablet system (SSTS) may reduce acute pain sufficientl...

    Authors: Michael Borck, Jan D. Wandrey, Claudia Spies and Sascha Tafelski
    Citation: Perioperative Medicine 2025 14:23
  32. The optimal fluid management strategy for patients undergoing on-pump cardiac surgery was controversial regarding the fluid types. This study aimed to compare the impact of hydroxyethyl starch (HES) and succin...

    Authors: Jing Wang, Luyu Bian, Tianlong Wang, Han Zhang, Jieru Zhang, Qiaoni Zhang, Gang Liu, Jian Wang, Yuan Teng, Zhenzhen Li, Shujie Yan and Bingyang Ji
    Citation: Perioperative Medicine 2025 14:22
  33. Hip fracture in the elderly is considered a significant public health burden due to a high rate of mortality and this is globally being seen as a serious concern. However, comorbidities requiring anticoagulant...

    Authors: Yuxi Wei, Chi Chen, Zhihong Yu and Jun Guo
    Citation: Perioperative Medicine 2025 14:21
  34. Remimazolam toluene sulfonic acid is a short-acting benzodiazepine primarily studied for intravenous anesthesia. To date, few studies have focused on the effects of the combination of remimazolam and inhalatio...

    Authors: Xiawei Lai, Shuxian Liu, Di Wang, Yuqing Chi, Xiaoqun Su, Lideng Guo, Zhijing Zhang and Haihui Xie
    Citation: Perioperative Medicine 2025 14:20
  35. This study aimed to evaluate the effect of perioperative real-time information sharing on family members’ anxiety in patients undergoing elective thoracoscopic lobectomy and to explore the potential role of in...

    Authors: Yun Linjun, Luo Xi, Ying Yanmei, Luo Wulajing, Fang Linjie, Kang Jingping and He Xiao
    Citation: Perioperative Medicine 2025 14:19
  36. Opioids are commonly used in general anesthesia for pain management. However, they are linked to significant side effects. Patients undergoing laparoscopic sleeve gastrectomy, particularly those with obesity, ...

    Authors: Hanane Barakat, Linda Gholmieh, Jessy Abou Nader, Vanda Yazbeck Karam, Obey Albaini, Mohamad El Helou and Rony Al Nawwar
    Citation: Perioperative Medicine 2025 14:16
  37. To investigate whether remote ischemic preconditioning (RIPC) could reduce the incidence of perioperative neurocognitive disorder (PND) in elderly patients undergoing major surgery (> 2 h), to assess the poten...

    Authors: Feifei Xu, Tingting Liu, Huiqing Liu, Jiao Deng, Shan He, Zhihong Lu, Haopeng Zhang and Hailong Dong
    Citation: Perioperative Medicine 2025 14:15
  38. It is common to observe a gap between the day on which the discharge criteria are reached and the actual day of discharge after colorectal surgery. The aim of this study is to understand the reasons for this d...

    Authors: Lorenzo Pandolfini, Duccio Conti, Piercarlo Ballo, Silvia Rollo, Alessandro Falsetto, Gian Matteo Paroli, Paolo Ciano, Michele Benedetti, Leonardo Antonio Montemurro, Giacomo Ruffo, Massimo Giuseppe Viola, Felice Borghi, Gianandrea Baldazzi, Massimo Basti, Pierluigi Marini, Mariano Fortunato Armellino…
    Citation: Perioperative Medicine 2025 14:14
  39. Postoperative delirium is a common and significant consequence in patients with type A aortic dissection following surgery; however, there is currently no effective postoperative care plan.

    Authors: Xueping Li, Miaomiao Zheng, Ailin Lin, Chaohong Chen, Yuanbo Wu, Huai Zhang and Zhiqin Yin
    Citation: Perioperative Medicine 2025 14:13
  40. The unfamiliar atmosphere of the operating room, waiting for anesthesia, and the process of surgery and anesthesia are some of the factors causing fear and anxiety in patients. It leads to physical and psychol...

    Authors: Nasim Alipour, Amir Jalali, Rostam Jalali and Alireza Khatony
    Citation: Perioperative Medicine 2025 14:11
  41. Subglottic stenosis is a significant clinical challenge in pediatric anesthesia, often necessitating interventions that can lead to various postoperative complications. The aim of this study was to determine t...

    Authors: Zeliha Tuncel, Şenay Göksu, Özlem Deligöz, Kemal Tolga Saracoglu, Abdulatif Albasha, Bushra M. Abdallah and Ayten Saracoglu
    Citation: Perioperative Medicine 2025 14:10
  42. This study aims to explore the analgesic effects and safety of periarticular injections of methylene blue (MB) combined with a cocktail formulation following total knee arthroplasty (TKA).

    Authors: Yijiang Deng, Yong Yang, Feng Zhu, Wenzhi Liu, Jiarui Chen and Guangmin Xu
    Citation: Perioperative Medicine 2025 14:9

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