Maxillofacial free flap surgery outcomes in critical care: a single-center investigation looking for clues to improvement

Table 6 Univariable analysis of predictors of infectious complications

*Variables*	Univariable OR (95% CI)	Univariable p-value
Age (years)	1.02 (1.00–1.05)	0.071
Sex	0.71 (0.32–1.51)	0.371
BMI (kg m⁻²)	0.97 (0.89–1.06)	0.499
< 18.5	2.03 (0.51–8.63)	0.312
Smoking history	2.01 (0.91–4.64)	0.090
Alcohol	3.02 (1.41–6.69)	0.005
Total reversible CV risk factors	1.55 (1.06–2.30)	0.025
CV disease	0.84 (0.35–1.95)	0.682
COPD	2.13 (0.77–6.04)	0.144
Chronic renal failure	0.74 (0.15–2.96)	0.680
Liver disease	0.24 (0.01–1.44)	0.188
Stroke	1.53 (0.18–13.15)	0.675
Charlson Comorbidity Index	1.13 (0.95–1.36)	0.184
ASA classification
II	1.71 (0.51–6.83)	0.406
III	2.29 (0.58–10.37)	0.252
Surgical indication
Delayed reconstruction	0.63 (0.11–3.51)	0.587
Osteoradionecrosis	0.87 (0.21–3.70)	0.838
Trauma	0.63 (0.02–9.16)	0.736
Others	0.63 (0.02–9.16)	0.736
Cancer context	1.76 (0.60–5.88)	0.323
Past head and neck radiotherapy	0.84 (0.34–2.02)	0.705
Past head and neck FF failure	7.50 (0.78–101.01)	0.092
Preoperative hemoglobin level (g/dL)	0.65 (0.45–0.90)	0.012
Fibula flap	1.52 (0.72–3.23)	0.274
Ischemia time (min)	1.01 (0.99–1.02)	0.270
Operative time (h)	1.40 (1.12–1.77)	0.004
Intraoperative IV fluids (mL.kg⁻¹.h⁻¹)	1.03 (0.91–1.16)	0.662
Intraoperative blood transfusion	2.39 (1.09–5.50)	0.034

Categorical variables are presented as n (%) and continuous variables as mean ± SD. Bold values are significant
BMI body mass index, COPD chronic obstructive pulmonary disease, CV cardiovascular, FF free flap, ICU intensive care unit, IV intravenous, LOS length of stay
Reversible cardiovascular risk factors include obesity, hypertension, dyslipidemia, diabetes, and active smoking

ISSN: 2047-0525