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Fig. 1 | Perioperative Medicine

Fig. 1

From: The impact of spinal anaesthesia on perioperative opioid consumption, postoperative pain and oncological outcome in radical retropubic prostatectomy—a retrospective before-and-after effectiveness study

Fig. 1

Kaplan–Meier curves of cancer-free survival after radical retropubic prostatectomy. Kaplan–Meier curves of cancer-free survival by study group and tumour stage (TNM classification, pT2: within the prostatic capsule, pT3 extracapsular extension) over time. In multivariable Cox regression analyses, the time to cancer recurrence was highly associated with TNM stage (p < 0.001, pT3 vs. pT2 hazard ratio 5.4 [95%CI 3.3; 9.2]), but not with group (p = 0.29), age (p = 0.737), ASA class (p = 0.935) and BMI (p = 0.779), and thus those four variables were excluded from the final model. Pairwise group comparisons between tumour stages were conducted by Kaplan–Meier analysis with log-rank test: pT2a vs. pT2c p = 0.211, pT2a vs. pT3a p = 0.06, pT2a vs. pT3b p = 0.01, pT2c vs. pT3a p < 0.01, pT2c vs. pT3b p < 0.01, pT3a vs. pT3b p < 0.01

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