Table 3 Predicted median oral morphine equivalent dose (mg)
From: Postoperative analgesia for upper gastrointestinal surgery: a retrospective cohort analysis
Direction of change in analgesia | Subgroup of surgery | Median difference in oral morphine equivalent dose (mg) | 95% Credible Interval | Probability | |
|---|---|---|---|---|---|
Increase in median OMED \(\ge 10mg\) | Reduction in median OMED \(\ge 10mg\) | ||||
Non-neuraxial to intrathecal morphine | Laparoscopic | -5.0 | -18.3 to 9.3 | 0.03 | 0.22 |
Open | -6.0 | -31.9 to 22.4 | 0.14 | 0.38 | |
Type 1 surgery | -6.2 | -31.1 to 20.0 | 0.11 | 0.38 | |
Type 2 surgery | -2.1 | -51.3 to 47.5 | 0.29 | 0.36 | |
Type 3 surgery | -4.6 | -18.6 to 9.5 | 0.03 | 0.22 | |
Intrathecal morphine to non-neuraxial | Laparoscopic | 3.5 | -22.8 to 33.8 | 0.31 | 0.17 |
Open | 4.4 | -23.2 to 37.5 | 0.37 | 0.16 | |
Type 1 surgery | 4.1 | -21.4 to 30.4 | 0.33 | 0.14 | |
Type 2 surgery | 7.1 | -53.2 to 71.5 | 0.46 | 0.28 | |
Type 3 surgery | 3.9 | -51.6 to 64.3 | 0.41 | 0.28 | |
Non-neuraxial to thoracic epidural analgesia | Laparoscopic | -38.5 | -47.2 to -29.4 | 0.00 | 1.00 |
Open | -67.2 | -86.3 to -47.2 | 0.00 | 1.00 | |
Type 1 surgery | -63.1 | -82.0 to -46.4 | 0.00 | 1.00 | |
Type 2 surgery | -48.5 | -99.6 to -11.8 | 0.00 | 0.98 | |
Type 3 surgery | -37.6 | -46.2 to -28.6 | 0.00 | 1.00 | |
Thoracic epidural analgesia to non-neuraxial | Laparoscopic | 27.1 | 5.8 to 58.6 | 0.94 | 0.00 |
Open | 66.3 | 41.5 to 97.3 | 1.00 | 0.00 | |
Type 1 surgery | 61.3 | 38.8 to 90.4 | 1.00 | 0.00 | |
Type 2 surgery | 68.6 | 37.1 to 107.7 | 1.00 | 0.00 | |
Type 3 surgery | 51.8 | 5.1 to 128.0 | 0.97 | 0.00 | |
Intrathecal morphine to thoracic epidural analgesia | Laparoscopic | -41.8 | -66.2 to -20.1 | 0.00 | 1.00 |
Open | -66.4 | -87.9 to -47.0 | 0.00 | 1.00 | |
Type 1 surgery | -56.6 | -74.4 to -38.5 | 0.00 | 1.00 | |
Type 2 surgery | -84.3 | -141.2 to -35.2 | 0.00 | 1.00 | |
Type 3 surgery | -61.1 | -115.4 to -15.6 | 0.00 | 0.99 | |
Thoracic epidural analgesia to intrathecal morphine | Laparoscopic | 21.7 | 0.4 to 50.4 | 0.87 | 0.00 |
Open | 62.7 | 40.5 to 92.5 | 1.00 | 0.00 | |
Type 1 surgery | 57.8 | 35.0 to 86.2 | 1.00 | 0.00 | |
Type 2 surgery | 64.8 | 35.5 to 100.7 | 1.00 | 0.00 | |
Type 3 surgery | 48.9 | -2.9 to 128.0 | 0.96 | 0.00 | |