Fig. 3

A Changing distribution of ASA scores of participants in RCTs over time, with real-world reference cohort top. B Change in percentage of ASA 1 and ASA 3 + participants recruited over time. Trendlines are 2-period moving average. Solid grey, % of participants ASA 3 + recruited to perioperative RCTs. Dotted grey, % of ASA 3 + patients in UCLH reference cohort. Solid blue, % of participants ASA 1 recruited to perioperative RCTs. Dotted blue, % of ASA 1 patients in UCLH reference cohort