Table 3 Multiple logistic regression analysis of factors associated with the inappropriate prophylactic use of PPIs during the perioperative period
Variable | Assignment | Adjusted OR (95% CI) | P |
|---|---|---|---|
Gender | Male = 0, female = 1 | 1.256 (0.649–2.430) | 0.499 |
Age | ≤ 65 = 0, > 65 = 1 | 1.098 (0.498–2.420) | 0.817 |
Intraoperative blood loss | < 1500 = 0, ≥ 1500 = 1 | 0.242 (0.027, 2.128) | 0.201 |
Antithrombotics | No = 0, yes = 1 | 0.313 (0.136–0.721) | 0.006 |
Systemic corticosteroids | No = 0 | ||
Low dose = 1 | 1.253 (0.366–4.295) | 0.720 | |
High dose = 2 | 1.049 (0.278–3.961) | 0.944 | |
Dosage form | Injectable = 0, oral = 1 | 18.301 (7.497–44.671) | < 0.001 |
Time of medical orders | Workday = 0, weekend = 1 | 0.998 | |
Types of medical orders | Standing = 0 | ||
Statim = 1 | 1.867 (0.780–4.470) | 0.161 | |
discharge = 2 | 11.739 (1.289–106.886) | 0.029 | |
Professional titles of doctors | Senior = 0 | ||
Middle = 1 | 1.477 (0.725–3.008) | 0.283 | |
Junior = 2 | 9.167 (3.459–24.299) | < 0.001 | |
Number of drugs | ≤ 10 = 0 | ||
11–20 = 1 | 0.605 (0.299–1.224) | 0.162 | |
> 20 = 2 | 0.818 (0.220–3.043) | 0.764 | |
Length of postoperative hospital stay | ≤ 7 = 0 | ||
8–15 = 1 | 0.515 (0.252–1.056) | 0.070 | |
> 15 = 2 | 0.262 (0.072–0.951) | 0.042 |