The use of transcutaneous electrical acupoint stimulation to reduce opioid consumption in patients undergoing off-pump CABG: a randomized controlled trial

Table 2 Primary outcome measurements of modified intention to treat set and per protocol set

Group	Regional group	Distal–proximal group	Sham group	Distal–proximal vs regional		Distal–proximal vs sham
MITT, n = 313	n = 104	n = 105	n = 104	Mean difference (95% CI)	p*	Mean difference (95% CI)	p*
Dose of sufentanil (μg)	339.5 (10.9)	303.9 (10.8)	338.8 (10.9)	− 35.5 (− 65.6, − 5.5)	0.020	− 34.9 (− 64.9, − 4.9)	0.023
PP, n = 306	n = 102	n = 104	n = 100
Dose of sufentanil (μg)	338.6 (11.0)	303.6 (10.9)	339.4 (11.1)	− 35.0 (− 65.4, − 4.6)	0.024	− 35.9 (− 66.4, − 5.3)	0.021

Abbreviations: SE standard error, MITT modified intention-to-treat analysis, PP per protocol
Values are marginal mean (SE)
^*Multiple pairwise comparisons were adjusted by Bonferroni approach with p < 0.025 considered as significant

ISSN: 2047-0525