Table 3 Second outcomes were analyzed in modified intention-to-treat analysis
Group | Regional group n = 104 | Distal–proximal group n = 105 | Sham group n = 104 | Distal–proximal vs regional | Distal–proximal vs sham |
|---|---|---|---|---|---|
SMD (95% CI) | SMD (95% CI) | ||||
Postoperative VIS at 24 h | 3.5 (2.0, 4.9) | 4.5 (2.0, 5.0) | 4.5 (2.7, 5.9) | 0.22 (− 0.05, 0.50) | 0.13 (− 0.14, 0,40) |
Dosage of propofol (mg) | 561.0 (359.5, 847.5) | 581.5 (383.5, 923.5) | 470.5 (274.8, 727.3) | 0.00 (− 0.27, 0.27) | 0.22 (− 0.06, 0.49) |
Length of mechanical ventilation (h) | 16.3 (8.8, 19.0) | 15.8 (7.8, 19.1) | 15.9 (10.8, 19.9) | 0.12 (− 0.15, 0.39) | 0.02 (− 0.25, 0.29) |
Length of CCU stays (h) | 40.0 (22.8, 46.0) | 41.0 (27.8, 45.1) | 41.0 (25.3, 67.8) | 0.05 (− 0.23, 0.32) | 0.19 (− 0.08, 0.46) |
Length of postoperative hospital stays (day) | 9.0 (7.0, 11.0) | 9.0 (7.0, 12.0) | 9.0 (8.0, 11.8) | 0.17 (− 0.10, 0.45) | 0.02 (− 0.26, 0.29) |
Postoperative complications, n (%) | |||||
 Myocardial infarction | 19 (18.3) | 27 (25.7) | 19 (18.3) | 0.18 (− 0.09, 0.46) | 0.16 (− 0.12, 0.43) |
 Cardiac dysfunction | 2 (1.9) | 4 (3.8) | 5 (4.8) | 0.16 (− 0.11, 0.43) | 0.00 (− 0.27, 0.28) |
 Delirium | 0 (0.0) | 1 (1.0) | 3 (2.9) | 0.14 (− 0.13, 0.41) | 0.15 (− 0.13, 0.42) |
 Stroke | 0 (0.0) | 2 (1.9) | 1 (1.0) | 0.20 (− 0.08, 0.47) | 0.08 (− 0.20, 0.35) |
 Acute kidney injury | 10 (9.6) | 12 (11.4) | 10 (9.6) | 0.06 (− 0.22, 0.34) | 0.06 (− 0.21, 0.34) |
 Liver dysfunction | 10 (9.6) | 19 (18.1) | 15 (14.4) | 0.25 (− 0.02, 0.53) | 0.10 (− 0.17, 0.38) |
 Pulmonary complication | 19 (18.3) | 21 (19.0) | 13 (12.5) | 0.04 (− 0.24, 0.31) | 0.20 (− 0.08, 0.48) |
 Infection | 20 (19.2) | 21 (19.0) | 18 (17.3) | 0.02 (− 0.26, 0.29) | 0.06 (− 0.22, 0.33) |
 Other complication | 2 (1.9) | 3 (2.9) | 0 (0.0) | 0.14 (− 0.14, 0.41) | 0.06 (− 0.22, 0.33) |
 Mortality within 30 days, n (%) | 1 (1.0) | 1 (1.0) | 3 (2.9) | 0.00 (− 0.27, 0.28) | 0.09 (− 0.19, 0.36) |