Establishment and validation of a risk prediction model for delayed neurocognitive recovery associated with cerebral oxygen saturation monitoring

Table 1 Demographics of patients undergoing laparoscopic colorectal cancer surgery in the training and validation cohorts

	Modelling group (n = 204)	Validation group (n = 25)	P value
Age, mean ± SD, year	62.99 ± 7.49	68.40 ± 4.90	0.015
Gender			0.123
Male, n (%)	133 (65.2%)	12 (48.0%)
Female, n (%)	71 (34.8%)	13 (52.0%)
BMI, mean ± SD, kg/m²	22.82 ± 2.94	23.46 ± 3.62	0.650
Years of Education, mean ± SD, year	9.09 ± 3.78	8.84 ± 3.80	0.941
Preop Hb, median (IQR), g/L	128 (115, 138)	112 (100.5, 127.5)	0.005
Intraop blood loss, median (IQR), mL	100 (50, 150)	100 (50, 175)	0.400
Duration of surg, mean ± SD, min	187.54 ± 79.89	177.80 ± 46.95	0.020
Intraoperative positioning			< 0.001
Head down, n (%)	115 (56.4%)	21 (84.0%)
Head up, n (%)	9 (4.4%)	4 (16.0%)
Supine position, n (%)	73 (35.8%)	0 (0%)
IAP, median (IQR), mmHg	15 (14, 15)	12.5 (12, 13)	< 0.001
Baseline rrSO₂, mean ± SD, %	64.39 ± 5.96	65.74 ± 5.05	0.426
Baseline lrSO₂, mean ± SD, %	64.54 ± 5.35	63.80 ± 3.83	0.034
lrSO₂ v, mean ± SD, %	11.14 ± 8.13	8.17 ± 6.08	0.480
rrSO₂ v, mean ± SD, %	13.45 ± 8.57	9.91 ± 6.53	0.167
Diabetes			0.756
No, n (%)	177 (86.8%)	21 (84.0%)
Yes, n (%)	27 (13.2%)	4 (16.0%)
Hypertension			0.481
No, n (%)	144 (70.6%)	20 (80.0%)
Yes, n (%)	60 (29.4%)	5 (20.0%)
CAD			1.000
No, n (%)	192 (94.1%)	24 (96.0%)
Yes, n (%)	12 (5.9%)	1 (4.0%)
DNR			0.021
No, n (%)	173 (84.8%)	16 (64.0%)
Yes, n (%)	31 (15.2%)	9 (36.0%)

The values are presented as means ± SD (standard deviation), median (interquartile range), or n (%) depending on type and distribution
IQR interquartile range, BMI body mass index, Preop Hb preoperative haemoglobin concentration, IAP intra-abdominal pressure, rSO2v the maximum variability of cerebral oxygen, CAD coronary artery disease, DNR delayed neurocognitive recovery

ISSN: 2047-0525