Table 3 Intraoperative data on blood loss and blood transfusion
Variable | All patients N = 129 | Single bolus (Group A) N = 60 | Bolus + infusion (Group B) N = 69 | Mean difference (95% confidence interval) | p-value |
|---|---|---|---|---|---|
Total TXA dose received, mg | 1782.53 ± 541.10 | 1344.85 ± 257.52 | 2163.12 ± 421.42 | − 818.27 (− 938.42 to − 698.12) | < 0.001 |
Intraoperative blood loss | |||||
mL | 696.88 ± 280.26 | 650.88 ± 267.31 | 736.87 ± 286.99 | − 85.99 (− 183.10 to 11.13) | 0.082 |
mL/spinal level | 66.00 ± 28.17 | 60.67 ± 22.08 | 70.63 ± 31.99 | − 9.96 (− 19.45 to − 0.48) | 0.040 |
mL/h | 388.73 ± 166.93 | 375.12 ± 149.84 | 400.57 ± 180.74 | − 25.45 (− 83.81 to 32.92) | 0.390 |
Sponge blood volumea, mL | 23.36 ± 21.77 | 26.67 ± 26.30 | 20.48 ± 16.53 | 6.19 (− 1.62 to 14.00) | 0.119 |
24-h postoperative drain | 77.83 ± 48.30 | 72.42 ± 43.56 | 82.54 ± 51.92 | − 10.12 (− 26.76 to 6.52) | 0.231 |
Total surgical blood loss (range)b | |||||
mL | 774.71 ± 294.86 (175.00–1607.00) | 723.30 ± 279.39 (175.00–1607.00) | 819.41 ± 302.60 (330.00–1556.00) | − 96.11 (− 198.12 to 5.91) | 0.065 |
mL/spinal level | 73.32 ± 29.76 (17.50–221.00) | 67.49 ± 22.31 (17.50–146.09) | 78.39 ± 34.33 (35.93–221.00) | − 10.90 (− 21.16 to − 0.64) | 0.037 |
mL/h | 432.37 ± 175.39 (140.00–1115.00) | 418.09 ± 153.52 (140.00–1115.00) | 444.79 ± 192.67 (174.00–1037.33) | − 26.70 (− 88.03 to 34.63) | 0.391 |
Cell salvage volume, mL | 321.12 ± 160.26 | 296.80 ± 147.06 | 342.26 ± 169.12 | − 45.46 (− 101.09 to 10.17) | 0.108 |
Total crystalloid volume | |||||
mL | 1151.94 ± 228.57 | 1132.50 ± 202.28 | 1168.84 ± 249.43 | − 36.34 (− 116.24 to 43.56) | 0.370 |
mL/kg | 26.64 ± 6.36 | 26.04 ± 6.17 | 27.16 ± 6.53 | − 1.12 (− 3.34 to 1.11) | 0.322 |
Allogenic blood transfusion | 0 (0) | 0 (0) | 0 (0) | ||