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Table 4 Laboratory data

From: Association of single bolus versus bolus followed by infusion of tranexamic acid with blood loss in adolescent idiopathic scoliosis surgery

Laboratory data

Single bolus (Group A)

Bolus + infusion (Group B)

p-value

Haemoglobin, g/dL

 T1

13.27 ± 1.09

13.70 ± 0.98

0.021

 T2

11.49 ± 1.15

11.85 ± 1.17

0.082

 T3

10.56 ± 1.10

10.66 ± 1.13

0.609

 T3-T1

 − 2.72 ± 0.99

 − 3.04 ± 1.10

0.081

Haematocrit, %

 T1

0.40 ± 0.03

0.42 ± 0.03

0.015

 T2

0.34 ± 0.03

0.35 ± 0.03

0.093

 T3

0.32 ± 0.03

0.33 ± 0.04

0.331

 T3-T1

 − 0.08 ± 0.03

 − 0.09 ± 0.04

0.316

International normalised ratio

 T1

1.09 ± 0.07

1.08 ± 0.08

0.602

 T2

1.22 ± 0.07

1.22 ± 0.08

0.745

 T3

1.24 ± 0.10

1.22 ± 0.09

0.204

 T3-T1

0.15 ± 0.11

0.14 ± 0.09

0.429

Activated partial thromboplastin time, s

 T1

35.41 ± 3.14

36.11 ± 3.88

0.262

 T2

35.23 ± 3.13

35.34 ± 3.96

0.868

 T3

31.27 ± 2.07

33.90 ± 4.52

 < 0.001

 T3-T1

 − 4.14 ± 3.24

 − 2.21 ± 3.97

0.003

Fibrinogen, g/L

 T1

2.66 ± 0.44

2.71 ± 0.50

0.557

 T2

2.14 ± 0.53

2.14 ± 0.73

0.994

 T3

4.72 ± 0.60

3.09 ± 1.38

 < 0.001

 T3-T1

2.06 ± 0.65

0.38 ± 1.44

 < 0.001

  1. Data shown are mean ± standard. T1, pre-operation; T2, 0-h post-operation; T3, 48-h post-operation. T3-T1, perioperative drift (pre-operation to 48-h post-operation)