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Table 1 Comparisons of baseline characteristics between the SH group and control group in the low- to moderate-risk (n = 508), and high- to very high-risk (n = 446) MRS group, respectively

From: Simplified rapid hydration and contrast-associated acute kidney injury among CKD patients stratified by Mehran score: sub-analysis from the TIME Trial

Variables

Low- to moderate-risk group

(n = 508)

High- to very high-risk group

(n = 446)

SH group

(n = 261)

Control group

(n = 247)

P

SH group

(n = 221)

Control group

(n = 225)

P

Age, years

67.9 (8.8)

66.9 (9.3)

0.2072a

71.3 (10.5)

70.6 (10.1)

0.4604a

Male, %

68 (26.1)

61 (24.7)

0.8031b

54 (24.4)

58 (25.8)

0.8275b

DM, n (%)

77 (29.5)

76 (30.8)

0.8302b

129 (58.4)

133 (59.1)

0.9501b

CHF, n (%)

21 (8.0)

17 (6.9)

0.7418b

108 (48.9)

102 (45.3)

0.5137b

CAD, n (%)

237 (90.8)

220 (89.1)

0.6150b

209 (94.6)

210 (93.3)

0.7271b

AMI, n (%)

36 (13.8)

32 (13.0)

0.8833b

38 (17.2)

46 (20.4)

0.4493b

Hypertension, n (%)

230 (88.1)

217 (87.9)

1.0000b

193 (87.3)

182 (80.9)

0.0837b

Scr, mg/dL

1.4 (0.2)

1.4 (0.2)

0.6103a

1.8 (0.5)

1.8 (0.5)

0.7444a

eGFR, mL/min/1.73 m2

51.1 (6.5)

51.2 (7.3)

0.9605a

40.0 (10.6)

40.0 (14.9)

0.9782a

BUN, mmol/L

8.0 (2.5)

7.5 (2.1)

0.0191a

10.6 (4.4)

10.5 (4.2)

0.8155a

CysC, mg/L

1.4 (0.4)

1.4 (0.4)

0.9416a

1.8 (0.5)

1.9 (0.6)

0.6082a

CRP, mg/L

16.6 (25.0)

27.6 (61.5)

0.3102a

17.1 (21.9)

24.7 (37.4)

0.2438a

BNP, pg/ml

264.2 (442.1)

261.8 (428.2)

0.9856a

399.2 (554.1)

478.4 (613.8)

0.5935a

LVEF, %

58.5 (9.8)

58.8 (11.6)

0.8181a

55.6 (12.5)

53.8 (13.1)

0.1731a

Anemia, n (%)

97 (37.2)

78 (31.6)

0.2184b

154 (69.7)

155 (68.9)

0.9369b

IABP, n (%)

0 (0.0)

0 (0.0)

NA

2 (0.9)

5 (2.2)

0.4605b

Non-PCI, %

149 (57.1)

111 (44.9)

0.0081b

111 (50.2)

105 (46.7)

0.5110b

CMV, mL

102.9 (67.3)

113.6 (65.1)

0.0706b

126.2 (81.5)

122.7 (68.6)

0.6219b

Periprocedural intravenous hydration volume, mL

1200.4 (619.1)

1601.7 (776.7)

 < 0.0001a

1072.4 (569.0)

1412.5 (674.1)

 < 0.0001a

Periprocedural urine volume, mL

1763.4 (1148.5)

1991.4 (1155.6)

0.0965a

1584.4 (962.9)

2135.0 (3803.5)

0.1021a

  1. Abbreviations: MRS Mehran risk score, DM diabetes mellitus, CHF congestive heart failure, CAD coronary artery disease, AMI acute myocardial infarction, Scr serum creatinine, eGFR estimate glomerular filtration rate, IABP intra-aortic balloon pump, CMV contrast media volume, PCI percutaneous coronary intervention, SH group simplified rapid hydration group, Control group, standard hydration group
  2. Values are mean ± SD, n (%), or median (IQR)
  3. aIndependent t-test
  4. bThe χ2 test