Table 2 Differential analysis and multivariate logistic regression analysis of the result of anastomotic leak and clinical candidate predictors in the training set

Sex (male/female)

1.21 [0.74; 1.94]

0.512

Age (years)

1.04 [1.01; 1.07]

0.004

1.036 (1.003–1.071)

0.034

Smoking history

 < 0.001

1.420 (1.096–1.841)

0.008

 None

-

 Moderate

0.66 [0.31; 1.30]

 Lots

2.19 [1.40; 3.45]

BMI (kg/m²)

0.98 [0.91; 1.05]

0.538

Weight (kg)

0.99 [0.97; 1.01]

0.368

GNRI

0.89 [0.87; 0.92]

 < 0.001

0.901 (0.873–0.931)

0.000

FEV1 (kg/m²)

0.70 [0.51; 0.97]

0.040

0.913 (0.611–1.363)

0.656

MVV (L)

0.99 [0.97; 1.00]

0.006

0.991 (0.977–1.005)

0.185

Alcohol consumption:

 < 0.001

1.385 (1.075–1.785)

0.012

 None

-

 Moderate

0.70 [0.23; 1.65]

 Lots

2.37 [1.52; 3.67]

Hypertension (no/yes)

1.21 [0.73; 1.96]

0.534

Diabetes (no/yes)

1.19 [0.55; 2.32]

0.802

CHD (no/yes)

1.09 [0.43; 2.36]

1.000

Neoadjuvant (no/yes)

1.27 [0.85; 1.93]

0.291

Location of tumor

0.270

 Upper

-

 Middle

1.33 [0.61; 3.38]

 Lower

0.95 [0.42; 2.43]

Position of anastomosis

0.018

3.253 (1.381–7.664)

0.007

 Neck

-

 Intrathoracic

2.79 [1.23; 5.88]

Duration of surgery (min)

1.00 [1.00; 1.00]

0.493

Blood loss (ml)

1.00 [1.00; 1.00]

0.978

Pathological staging

0.322

 0

-

 1

0.51 [0.24; 1.12]

 2

0.73 [0.36; 1.59]

 3

0.55 [0.27; 1.19]

 4

0.80 [0.20; 2.67]

Number of lymph node dissection

0.99 [0.97; 1.00]

0.098

Vascular invasion (no/yes)

1.06 [0.63; 1.74]

0.927

Nerve infiltration (no/yes)

1.173 [0.752–1.829]

0.556

Hospitalization days (day)

1.14 [1.11; 1.16]

 < 0.001

Neck extubation (day)

1.10 [1.06; 1.14]

0.001

Surgical methods

0.751

 Thoracoscope

-

 DVSS

1.13 [0.66; 1.87]