Changes of perioperative cognitive function and its effect on quality of life in laryngeal cancer

Table 4 Comparison of quality of life (QLQ-C30) between patients with postoperative cognitive impairment and those with normal cognitive function

Items	Cognitive impairment group (n = 47)	Normal cognitive function group (n = 41)	t (95%CI)	p
Overall health function scale	58.94 ± 10.92	64.15 ± 11.20	2.203 (0.507–9.913)	0.030*
Body	69.21 ± 11.83	79.83 ± 11.75	4.216 (5.609–15.624)	< 0.001*
Cognition	61.89 ± 11.83	71.83 ± 8.58	4.055 (5.065–14.806)	< 0.001*
Role	73.23 ± 11.32	79.78 ± 16.62	2.182 (0.583–12.510)	0.032*
Emotion	73.43 ± 12.32	81.59 ± 13.74	2.916 (2.593–13.727)	0.005*
Social symptom scale	75.51 ± 11.31	80.34 ± 9.92	2.135 (0.334–9.328)	0.036*
Fatigue	35.87 ± 7.67	33.27 ± 5.97	− 1.788 (− 5.500–0.291)	0.077
Nausea and vomiting	18.38 ± 6.43	17.32 ± 5.40	− 0.845 (− 3.574–1.442)	0.401
Pain	18.26 ± 5.17	17.07 ± 4.55	− 1.141 (− 3.242–0.878)	0.257
Dyspnea	23.38 ± 6.84	24.37 ± 6.91	0.669 (− 1.941–3.906)	0.506
Insomnia	23.43 ± 6.97	24.37 ± 6.91	− 3.710 (− 7.621 to − 2.303)	< 0.001*
Decreased appetite	19.40 ± 5.04	15.63 ± 4.04	− 3.892 (− 5.696 to − 1.844)	< 0.001*
Constipation	20.38 ± 5.91	21.32 ± 5.53	0.766(− 1.490–3.358)	0.446
Diarrhea	28.34 ± 7.65	28.32 ± 6.71	− 0.015(− 3.065–3.018)	0.988
Financial difficulties	32.32 ± 8.11	31.83 ± 5.98	− 0.318(− 3.549–2.569)	0.751

ISSN: 2047-0525