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Table 2 Univariate and multivariate logistic regression models for the association between NT-proBNP and AKI risk

From: Association between the preoperative N-terminal pro-B-type natriuretic peptide and acute kidney injury in gastrointestinal surgery patients managed with enhanced recovery strategy: a retrospective cohort study

NT-proBNP (pg/mL)

 

Low level (< 165.0) (N = 314)

High level (≥ 165.0) (N = 315)

 

Low level (< 165.0) (N = 314)

High level (≥ 165.0) (N = 315)

Median (IQR)

62.0 (35.3 to 106.1)

428.6 (260.1 to 372.4)

 

62.0 (35.3 to 106.1)

428.6 (260.1 to 372.4)

Model 1a

Ref

1.56 (1.03 to 2.36)

Stage 1

Ref

0.74 (0.44 to 1.26)

Stage 2

Ref

1.10 (0.52 to 2.29)

Stage 3

Ref

0.64 (0.26 to 1.59)

Model 2b

Ref

1.75 (1.13 to 2.73)

Stage 1

Ref

0.75 (0.42, 1.35)

Stage 2

Ref

1.24 (0.56, 2.74)

Stage 3

Ref

0.51 (0.19, 1.35)

Model 3c

Ref

1.57 (0.98 to 2.52)

Stage 1

Ref

0.66 (0.36, 1.22)

Stage 2

Ref

1.24 (0.55, 2.84)

Stage 3

Ref

0.51 (0.18, 1.41)

Model 4d

Ref

1.49 (0.92 to 2.40)

Stage 1

Ref

0.66 (0.36 to 1.22)

Stage 2

Ref

1.29 (0.56 to 3.00)

Stage 3

Ref

0.53 (0.19 to 1.49)

Model 5e

Ref

1.43 (0.87 to 2.34)

Stage 1

Ref

0.65 (0.35 to 1.20)

Stage 2

Ref

1.28 (0.55 to 3.00)

Stage 3

Ref

0.59 (0.21 to 1.68)

  1. Abbreviations: NT-proBNP N-terminal pro-B-type natriuretic peptide, AKI acute kidney injury. aNon-adjusted model adjusted for none. bModel 2 adjusted for age, sex and BMI. cModel 3 adjusted for hemoglobin, creatinine, serum albumin, and covariates included in model 2. dModel 4 adjusted for and estimated blood loss, duration of surgery, urine output, intraoperative diuretics, intraoperative NSAIDs, intraoperative antibiotics, postoperative infections, and covariates included in model 3. eFully adjusted model adjusted for all covariates. Stage 1 means patients who were diagnosed as stage 1 AKI according to KDIGO 2021 guideline. Stage 2 means patients who were diagnosed as stage 2 AKI according to KDIGO 2021 guideline. Stage 3 means patients who were diagnosed as stage 3 AKI according to KDIGO 2021 guideline. KDIGO, Kidney Disease: Improving Global Outcomes